I always get the rebuttal, "But then there is no meaning."
But meaning or purpose is not necessary for life to exist. We do not through carbon and meaning into a soup to get life.
And the infamous, "How could this all happen by chance?"
I want to shoot whoever first said this, because 'chance' is an entirely wrong word to use.
Life, the Universe, and Everything did not happen "by chance."
There are laws and rules to the universe that make it, at least in some degree, intelligible. These things are not a matter of chance.
They are a matter of physics.
The fact is, matter and energy do not care about our 'feelings'--truth is what is, not what one might wish it to be.
Why does everyone think this is such a gloomy message? Can't people see how amazing REALITY is, without needing to put themselves at the center of it all?
I don't consider this at all dark or even undesirable. On the contrary, it is a much more fulfilling idea than any god that has ever been proposed.
This means that we are truly free.